2022年1月13日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就贝莱斯芽孢杆菌（Bacillus velezensis）DSM 15544作为奶牛和其他反刍动物饲料添加剂的安全性和有效性。

经过评估，专家小组认为该添加剂对目标物种、消费者和环境都是安全的。该添加剂不是皮肤/眼睛刺激物或皮肤敏化剂，但应被视为呼吸敏化剂。根据所提供的数据，专家小组不能就贝莱斯芽孢杆菌DSM 15544对奶牛或其他反刍动物的功效做出结论。

部分原文报道如下：

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the assessment of Calsporin? (Bacillus velezensis DSM 15544) as a zootechnical additive for dairy cows and other dairy ruminants. The product under assessment is based on viable spores of Bacillus velezensis DSM 15544. B. velezensis is considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The identity of the active agent was established and compliance with the applicable qualifications /confirm/ied. Therefore, B. velezensis DSM 15544 is presumed safe for the target species, consumers of products derived from animals fed the additive and the environment. Since no concerns are expected from the other components of the additive, Calsporin? is also considered safe for the target species, consumers of products derived from animals fed the additive and the environment. The additive is not a dermal/eye irritant or a skin sensitiser but should be considered a respiratory sensitiser. The FEEDAP Panel is not in the position to conclude on the efficacy of Calsporin? for dairy cows or other dairy ruminants based on the data provided.