2021年11月8日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就贝莱斯芽孢杆菌（Bacillus velezensis）DSM 15544作为仔猪(哺乳和断奶)、育肥猪、母猪、观赏鱼、狗和所有禽类饲料添加剂的安全性和有效性。

经过评估，专家小组认为该添加剂对目标物种、消费者和环境都是安全的。该添加剂不是皮肤/眼睛刺激物或皮肤敏化剂，但应被视为呼吸敏化剂。在3×108 CFU/kg饲料的水平下，该添加剂可能对所有禽类的饲养、育肥、产蛋和繁殖都有效。

部分原文报道如下：

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Bacillus velezensis DSM 15544 (Calsporin®) when used as a feed additive for piglets (suckling and weaned), pigs for fattening, sows in order to have benefit in piglets, ornamental fish, dogs and all avian species. The additive is authorised for use in sows, suckling and weaned piglets, pigs for fattening, chickens for fattening, laying hens, ornamental fish and dogs. With this application the company requested a new authorisation for all avian species and the modification of the current authorisations as regards the strain taxonomy from Bacillus subtilis DSM 15544 to B. velezensis DSM 15544. The FEEDAP Panel concluded that the active agent of Calsporin® should be taxonomically designated as Bacillus velezensis DSM 15544. The Panel also concluded that Calsporin® is presumed safe for the target species, consumers and the environment. Calsporin® is not a dermal/eye irritant or a skin sensitiser but should be considered a respiratory sensitiser. Calsporin® when supplemented at 3×108 CFU/kg complete feed has the potential to be efficacious in all avian species for rearing, fattening, laying and breeding purposes.